Subject: Computer and information sciences
Subject: Health sciences
Year: 2023
Type: Article
Type: PeerReviewed
Title: Principal Component Analysis to evaluate the stability impact of protein mutations: the case of SARS-CoV-2 K417T mutation
Author: Stojanov, Done
Author: Glavas Dodov, Marija
Author: Velinov, Aleksandar
Author: Nestorovska, Martina
Abstract: The severe acute respiratory syndrome CoV-2 (SARS CoV-2), which was initially identified in the Wuhan Province, China spread worldwide rapidly. The intense escalation forced the WHO to declare a pandemic with 6.5 million deaths worldwide. The purpose of this study was to examine and analyze the impact of K417T mutation upon SARS-CoV-2 S-protein/hACE2 complex stability through the process of PCA analysis.
Publisher: Macedonian Pharmaceutical Association & Ss. Cyril and Methodius University in Skopje, Faculty of Pharmacy
Relation: https://eprints.ugd.edu.mk/32265/
Identifier: oai:eprints.ugd.edu.mk:32265
Identifier: https://eprints.ugd.edu.mk/32265/1/69_3_133.pdfIdentifier: Stojanov, Done and Glavas Dodov, Marija and Velinov, Aleksandar and Nestorovska, Martina (2023) Principal Component Analysis to evaluate the stability impact of protein mutations: the case of SARS-CoV-2 K417T mutation. Macedonian pharmaceutical bulletin, 69 (Sup 1). pp. 273-274. ISSN 1857 - 8969
Identifier: 10.33320/maced.pharm.bull.2023.69.03.133
