Subject: R Medicine (General)
Year: 2023
Type: Article
Type: NonPeerReviewed
Title: A REVIEW OF COUMARIN DERIVATIVES IN PHARMACOTHERAPY
Author: BALLAZHI, Lulzime
Author: Alili Idrizi, Edita
Author: DAUTI, Merita
Author: Rustemi Ahmeti, Hanife
Author: Yzeiri Havziu, Drita
Abstract: Coumarins are proven precursors in the synthesis of many medicinal compounds and the heterocycles derived from them are widely appreciated for their numerous pharmacological effects. Molecules containing coumarin rings have been studied for their antiviral, antimicrobial, antifungal, anti-inflammatory, anticonvulsant, anticoagulant, antipsychotic, and anticancer effects. Thus, the isolation, structural characterization, and pharmacological evaluation of new derivatives combining coumarin rings continuously provoke research interest. In this paper, a brief overview of the chemical, biopharmaceutical, pharmacokinetic, and pharmacological properties, as well as the structure-activity relationship for many coumarin derivatives, is given, with a special focus on new compounds as potential chemotherapeutics or key components for the synthesis of drugs intended for the treatment of cancer.
Publisher: Faculty of Medical Sciences, Tetova
Relation: https://eprints.unite.edu.mk/1215/
Identifier: oai:eprints.unite.edu.mk:1215
Identifier: https://eprints.unite.edu.mk/1215/1/Acta%20Medica%20Balkanica2023-234-243.pdfIdentifier: BALLAZHI, Lulzime and Alili Idrizi, Edita and DAUTI, Merita and Rustemi Ahmeti, Hanife and Yzeiri Havziu, Drita (2023) A REVIEW OF COUMARIN DERIVATIVES IN PHARMACOTHERAPY. ACTA MEDICA BALKANICA International Journal of Medical Sciences, 8 (15-16). pp. 234-243. ISSN 2545 - 4870
