Subject: Hypofibrinogenaemia
Subject: pregnancy
Subject: peripartal management
Year: 2020
Type: Article
Title: Multidisciplinary approach to management of hypofibrinogenemia in pregnancy: a case report
Author: Slagjana Simeonova Krstevska
Author: Elizabeta Todorovska
Author: Tatjana Makarovska Bojadjieva
Author: Elena Petkovikj
Author: Saso Stojcevski
Author: Igor Samardjiski
Author: Saso Spasovski
Author: Violeta Dejanova
Author: Radica Grubovic
Author: Florije Raka
Author: Viktorija Jovanovska
Author: Irena Todorovska
Author: Vesna Livrinova
Author: Aneta Sima
Author: Sasa Jovcevski
Author: Daniel Milkovski
Abstract: Inherited fibrinogen disorders introduce risk for recurrent abortions, sub-chorionic haematoma, placental abruption and postpartum haemorrhage. This is a case report of a successful pregnancy outcome in a 37-year old woman with hypofibrinogenaemia. She was referred to a coagulation test in the first trimester because of history of preeclampsia and HELLP syndrome in previous pregnancy. Hypofibrinogenaemia was diagnosed with fibrinogen level of 0.7 g/L. During the pregnancy she was regularly monitored for fibrinogen levels and multiple cryoprecipitate concentrates were given. She delivered at 39th gestation week, with elective caesarean section under general anaesthesia. There was one episode of postpartum haemorrhage treated with 2 units of red blood cells, repeated infusions of cryoprecipitate to obtain the level of fibrinogen of 2 g/L. She was discharged on the 6th postpartum day in a good condition. In these disorders levels of fibrinogen should be higher than 1 g/L during pregnancy or 2 g/L in case of caesarean section for successful prenatal and peripartal management.
Publisher: Društvo doktora medicine Republike Srpske, Banja Luka i Univerzitet u Banjoj Luci - Medicinski fakultet, Banja Luka
Relation: SCRIPTA MEDICA
Identifier: oai:repository.ukim.mk:20.500.12188/9855
Identifier: http://hdl.handle.net/20.500.12188/9855Identifier: 10.5937/scriptamed51-26499
