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Year: 2008


Type: Article



Title: Effect of simvastatin in apolipoprotein E deficient mice with surgically induced chronic renal failure


Author: Ivanovski, Ognen
Author: Szumilak, Dorota
Author: Nguyen-Khoa, Thao
Author: Nikolov, Igor G
Author: Joki, Nobuhiko
Author: Mothu, Nadya
Author: Maizel, Julien
Author: Westenfeld, Ralf
Author: Ketteler, Marcus
Author: Lacour, Bernard
Author: Drüeke, Tilman B
Author: Massy, Ziad A



Abstract: Patients with a surgically reduced renal mass are at increased risk for progressive renal failure, which often requires renal replacement therapy or kidney transplantation. We investigated the effects of simvastatin supplementation on uremia enhanced atherosclerosis and vascular calcification in apoE(-/-) (apolipoprotein E deficient) mice (Charles Rivers Laboratories, Wilmington, Massachusetts) with or without superimposed chronic kidney disease.


Publisher: Ovid Technologies (Wolters Kluwer Health)


Relation: The Journal of urology



Identifier: oai:repository.ukim.mk:20.500.12188/9601
Identifier: http://hdl.handle.net/20.500.12188/9601
Identifier: 10.1016/j.juro.2007.11.042
Identifier: http://api.elsevier.com/content/article/PII:S0022534707030819?httpAccept=text/xml
Identifier: http://api.elsevier.com/content/article/PII:S0022534707030819?httpAccept=text/plain
Identifier: 179
Identifier: 4



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Effect of simvastatin in apolipoprotein E deficient mice with surgically induced chronic renal failure200816