Year: 2018
Type: Article
Title: Efficacy of Intraperitoneal Bupivacaine on Pain Relief After Laparoscopic Cholecystectomy
Author: Toleska, Marija
Author: Andrijan Kartalov
Author: Biljana Kuzmanovska
Author: Panovski, Milcho
Author: Mirjana Shosholcheva
Author: Dimitrovski, Aleksandar
Author: CHolanchevski, Risto
Author: Toleska, Natasha
Author: Zdravkovska, Milka
Abstract: Patients undergoing laparoscopic cholecystectomy do experience postoperative pain, especially in the abdomen. Postoperative pain management remains a major challenge after laparoscopic procedures. Administration of intraperitoneal local anesthetic (IPLA) after surgery is used as a method of reducing postoperative pain. In this study, we evaluated the effect of intraperitoneal infiltration of local anesthetic (bupivacaine) for pain relief after laparoscopic cholecystectomy.
Material and methods: In this prospective, controlled, and randomized study were included 50 patients aged 25-60 years (35 female and 15 male), scheduled to laparoscopic cholecystectomy with ASA classification 1 and 2. Patients were classified randomly into two groups: group A, which included 25 patients who received intraperitoneal instillation of bupivacaine 0.5% 20 ml; and group B, which included 25 patients who didn’t receive any intraperitoneal instillation. Postoperative pain was recorded using the visual analogue scale (VAS) for 24 hours after laparoscopic cholecystectomy. Results: There was no significant difference with respect to age, weight, and sex; duration of surgery; and anesthesia time. VAS scores at different time intervals were statistically significantly lower at all times in group A compared to group B. There were statistically significant differences in VAS scores between group A and group B at all postoperative time points - 1hr,4 hr,8 hr,12hr and 24hr (p < 0.00001). Conclusion: Intraperitoneal instillation of bupivacaine provides good analgesia in the postoperative period after laparoscopic cholecystectomy.
Publisher: Macedonian Academy of Sciences and Arts /Walter de Gruyter GmbH
Relation: Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki)
Identifier: oai:repository.ukim.mk:20.500.12188/9039
Identifier: 1857-9345
Identifier: http://hdl.handle.net/20.500.12188/9039Identifier: 10.2478/prilozi-2018-0032
Identifier: http://content.sciendo.com/view/journals/prilozi/39/1/article-p123.xmlIdentifier: http://www.degruyter.com/view/j/prilozi.2018.39.issue-1/prilozi-2018-0032/prilozi-2018-0032.pdfIdentifier: 39
Identifier: 1
