Year: 2015
Type: Article
Title: Sentinel Lymph Node Detection in Breast Cancer – First Experience
Author: Stojanoski, Sinisa
Author: Ristevska, Nevena
Author: Pop Gjorcheva, Daniela
Author: Antevski, Borce
Author: Petrushevska, Gordana
Abstract: Abstract Introduction: Breast cancer accouns for 22.9% of all cancers in women and 13.7% of cancer deaths. Positive axillary lymphnodes (ALN) predict the development of distant metastases. The status of the sentinel lymphnode (SLN) is crutial for the treatment selection. Aim: To determine the benefits of SLN detection in patients with breast cancer. Material and methodology: 38 female patients (pts), age 44 ± 12 years, with T1-2 N0 M0 breast cancer, without enlarged ALN on ultrasound (US), were included. SLN detection was performed using gamma camera and gamma detection probe after periareolar subcutaneous and/or peritumoral injection of (99m-Technetium-SENTISCINT). Blue dye was administered 20 min before the operation. SLN was extirpated and ex tempore histopathology was performed. Results: Ex tempore SLN evaluation was negative and the lymphatic pathways preserved in 28/38 (74%) pts. In 10/38 (26%) pts SLN was positive, followed by radical surgery. In 3/28 ex tempore negative patients, histopathological analysis showed metastatic involvement (false negative). In 3/10 ex tempore positive patients micro metastases 0,2-2 mm were detected. 12 pts had 2 SLN, 8/12 (66%) had negative and 4/12 (34%) had positive SLN. 3 pts had a rare double drainage to axilla and a. mammaria int. Conclusion: Our results confirm that SLN detection technique is non-invasive, safe and reliable and should be incorporated into the guidelines for breast cancer pts (T1-2 N0 M0). The most reliable option for colloid application is the combined technique of periareolar and peritumoral injection. Patients with drainage to a. mammaria interna should be selected for adjuvant protocols.
Publisher: Macedonian Academy of Sciences and Arts / Walter de Gruyter GmbH
Relation: Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki)
Identifier: oai:repository.ukim.mk:20.500.12188/8820
Identifier: http://hdl.handle.net/20.500.12188/8820Identifier: 10.1515/prilozi-2015-0039
Identifier: http://content.sciendo.com/view/journals/prilozi/36/1/article-p145.xmlIdentifier: https://www.degruyter.com/view/j/prilozi.2015.36.issue-1/prilozi-2015-0039/prilozi-2015-0039.pdfIdentifier: 36
Identifier: 1
