Subject: left atrial appendage
Subject: thrombus
Subject: sinus rhythm
Subject: dilated cardiomyiopathy
Year: 2013
Type: Article
Title: Prevalence of Left Chamber Cardiac Thrombi in Patients with Dilated Left Ventricle at Sinus Rhythm: The Role of Transesophageal Echocardiography
Author: Bakalli, A
Author: Georgievska-Ismail Lj
Author: Kocinaj, D
Author: Musliu, N
Author: Krasniqi, A
Author: Pilana, E
Abstract: Background: Left atrial appendage (LAA) may be a source of thrombi in patients with dilated cardiomyopathy at sinus rhythm. The objectives of our study were to assess the prevalence of intracardiac left chamber thrombus and/or spontaneous echo contrast and to identify clinical and echocardiographic predictors for left ventricle (LV), left atrium (LA), and/or LAA thrombus formation, particularly as regard to LV, LA, and LAA size, in heart failure patients at sinus rhythm. Methods: We included 45 patients with dilated cardiomyopathy of ischemic or idiopathic origin with mild to moderate systolic dysfunction, who were at sinus rhythm and without anticoagulation therapy. Results: Mean left ventricular end diastolic diameter was 64.9 ± 6.1 mm, and mean LV ejection fraction was 39.9 ± 7.3%. LV thrombus was found in 13.3% of patients and LAA thrombus in 68. 9%. Left ventricular end diastolic diameter was correlated with LA volume (r = 0.59, p < 0.0001) and LV thrombus (r = 0.38, p = 0.005). LA volume was correlated with LAA maximal area (r = 0.34, p = 0.01), which was an independent predictor for LAA thrombus formation (p = 0.003). Conclusions: Dilation of left cardiac chambers offers a suitable terrain for thrombus formation. The high probability of LAA thrombosis should be kept in mind when designing the treatment strategy for patients with dilated cardiomyopathy at sinus rhythm.
Publisher: Wiley Online Library
Relation: Journal of clinical ultrasound
Identifier: oai:repository.ukim.mk:20.500.12188/8701
Identifier: http://hdl.handle.net/20.500.12188/8701Identifier: 10.1002/jcu.21953
