Subject: granular cell tumor
Subject: rare benign neoplasm
Subject: cytoplasmic granule
Year: 2009
Type: Article
Title: Granular cell tumor of the breast: a case report and review of literature
Author: Filipovski, Vanja
Author: Banev, Saso
Author: Janevska, Vesna
Author: Dukova, Blagica
Abstract: A 22-year-old female patient presented with a breast mass lesion with a clinical suspicion of a fibroadenoma. Histological evaluation revealed a rare benign neoplasm - granular cell tumor. Granular cell tumor is rare neoplasm that may arise in virtually any body site, and in 5% it occurs in the breast. The histogenesis of this tumor is still rather controversial and currently the most acceptable theory is a Schwann cell origin. The main histological feature is granular cytoplasm of the tumor cells. From a clinical point of view there is a similarity between granular cell tumor and mammary carcinoma on mammography and ultrasound. Pathohistologically, sometimes, differential diagnostic difficulties exist concerning apocrine carcinoma, histiocytic lesions and metastatic neoplasms.
Publisher: BioMed Central
Relation: Cases Journal
Identifier: oai:repository.ukim.mk:20.500.12188/8407
Identifier: http://hdl.handle.net/20.500.12188/8407Identifier: https://doi.org/10.4076/1757-1626-2-8551
