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Year: 2018


Type: Article



Title: Tertiary Lymphoid Structures in Colorectal Cancers and Their Prognostic Value


Author: Trajkovski, Gjorgji
Author: Ognjenovic, Ljubomir
Author: Karadzov, Zoran
Author: Jota, GJorgji
Author: Hadzi-Manchev, Dragan
Author: Ognen Kostovski
Author: Volcevski, Goce
Author: Trajkovska, Vanja
Author: Nikolova, Dafina
Author: Spasevska, Liljana
Author: Janevska, Vesna
Author: Janevski, Vlado



Abstract: Tumor-infiltrating lymphocytes (TIL) in tumour stroma are considered to be involved in the elimination of malignant cells and prevention of metastasis formation. TIL consist of T lymphocytes including cytotoxic lymphocytes that are a constituent part of the effector mechanism of anti-tumour immunity and B lymphocytes that can form tertiary lymphoid structures (TLS). TLS has been described in several solid tumours and colorectal carcinoma (CRC), and the influence on the local and systemic anti-cancer response.


Publisher: ID Design 2012/DOOEL Skopje


Relation: Open Access Macedonian Journal of Medical Sciences



Identifier: oai:repository.ukim.mk:20.500.12188/7566
Identifier: 1857-9655
Identifier: http://hdl.handle.net/20.500.12188/7566
Identifier: 10.3889/oamjms.2018.341
Identifier: https://www.id-press.eu/mjms/article/download/oamjms.2018.341/2497
Identifier: https://www.id-press.eu/mjms/article/download/oamjms.2018.341/2525
Identifier: 6
Identifier: 10
Identifier: 1824
Identifier: 1828



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Tertiary Lymphoid Structures in Colorectal Cancers and Their Prognostic Value201827