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Subject: asthma
Subject: children
Subject: diagnosis
Subject: international
Subject: westernization
Subject: wheeze


Year: 2018


Type: Proceeding article



Title: Risk Factors for Childhood Asthma and Wheeze: Comparisons from an International Study


Author: Lawson, Joshua
Author: Brozek, Grzegorz Marek
Author: Emilija Vlaski
Author: Beridze, Vakhtangi
Author: Shpakov, Andrei
Author: Fedortsiv, Olga
Author: Rennie, Donna
Author: Afanasieva, Anna
Author: Beridze, Sophio
Author: Zejda, Jan Eugeniusz



Abstract: Background: There is variation in childhood asthma between countries with typically higher prevalence in “Westernized” nations. We compared asthma, respiratory symptoms, and medication prevalence in Eastern and Central European regions and Canada. Methods: We conducted a cross-sectional survey study of children (5–15 years) from one urban centre in each of Canada, Belarus, Poland, Republic of Georgia (Adjara), Republic of Macedonia, and Ukraine. Surveys were distributed through randomly selected schools to parents (2013–2015). Results: The prevalence of asthma differed by country from 20.6% in Canada to 1.5% in Ukraine (p < 0.001). This association remained after confounder adjustment. Except for Canada (58.7%) and Poland (42.5%), less than 10% of children with a history of wheeze had a diagnosis of asthma. Regardless of country, more than 50% of children with a diagnosis of asthma used breathing medications in the past year. Finally, except for Georgia (12.1%), all countries had a prevalence of ever wheeze above 20% (23.8% in Poland to 30.9% in Macedonia). Conclusions: Despite large differences in asthma prevalence, respiratory morbidity was more comparable suggesting asthma prevalence may be underestimated. Further validation of asthma diagnosis is needed. It is important to promote best diagnostic practices among first contact physicians.


Publisher: Research Triangle Park, N. C. National Institute of Environmental Health Sciences


Relation: Geographic variation related to asthma diagnosis, prevalence, and severity



Identifier: oai:repository.ukim.mk:20.500.12188/7475
Identifier: http://hdl.handle.net/20.500.12188/7475
Identifier: 10.1289/isesisee.2018.p03.2830
Identifier: 2018
Identifier: 1



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Risk Factors for Childhood Asthma and Wheeze: Comparisons from an International Study201842