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Subject: adolescents
Subject: asthma
Subject: atopic eczema
Subject: body mass index
Subject: overweight


Year: 2006


Type: Journal Article



Title: Overweight hypothesis in asthma and eczema in young adolescents


Author: E Vlaski
Author: Stavric, Katerina
Author: Isjanovska, Rozalinda
Author: Seckova, Lidija
Author: Kimovska, Milica



Abstract: BACKGROUND: A positive association between body mass index (BMI) and allergic diseases has recently been suggested; however the sex-dependence of this association remains controversial. The aim of the present study was to explore the relationship between BMI and asthma and eczema, as well as its sex-dependence in young adolescents. METHODS: Self-reported data obtained through the standardized International Study of Asthma and Allergies in Childhood (ISAAC) Phase Three written questionnaires of 2926 young adolescents aged 13-14 years old from randomly selected schools in Skopje (Republic of Macedonia) were used. The BMI for each individual was calculated and used-both unadjusted and adjusted for confounding factors-as a variable for analysis. The international cut-off points for BMI for overweight and obesity by sex and age were used. Because of the very low prevalence of obesity (1.5 %), obese respondents were included in the overweight group. The data were statistically analyzed by the chi-square test, the t-test for independent samples and odds ratios (OR, 95 % CI) in binary logistic regression. RESULTS: Being overweight was significantly associated with an increased risk of having a dry night cough without a cold or chest infection (adjusted OR: 1.54; 95 % CI: 1.09-2.16; p = 0.01) and with having had self-reported asthma at some time (adjusted OR: 2.36; 95 % CI: 1.02-5.44; p = 0.04) in boys only. A significant association between overweight and other symptoms of asthma or atopic eczema was not established. CONCLUSION: These findings suggest a male-specific positive association between overweight and a current dry night cough and having received a diagnosis of asthma at some time. No association was found with other asthma symptoms or atopic eczema in young adolescents.


Publisher: Elsevier BV


Relation: International Study of Asthma and Allergies in Childhood (ISAAC) Phase Three



Identifier: oai:repository.ukim.mk:20.500.12188/7390
Identifier: 0301-0546
Identifier: http://hdl.handle.net/20.500.12188/7390
Identifier: 10.1157/13094027
Identifier: https://api.elsevier.com/content/article/PII:S030105460673542X?httpAccept=text/xml
Identifier: https://api.elsevier.com/content/article/PII:S030105460673542X?httpAccept=text/plain
Identifier: 34
Identifier: 5
Identifier: 199
Identifier: 205



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Overweight hypothesis in asthma and eczema in young adolescents200631