Year: 2015
Type: Article
Title: Circulation of Crimean-Congo Hemorrhagic Fever Virus in the former Yugoslav Republic of Macedonia revealed by screening of cattle sera using a novel enzyme-linked immunosorbent assay
Author: Mertens, Marc
Author: Vatansever, Zati
Author: Mrenoshki, Slavcho
Author: Krstevski, Kiril
Author: Stefanovska, Jovana
Author: Djadjovski, Igor
Author: Cvetkovikj, Iskra
Author: Farkas, Robert
Author: Schuster, Isolde
Author: Donnet, Fabien
Author: Comtet, Loic
Author: Tordo, Noël
Author: Ben Mechlia, Mohamed
Author: Balkema-Buschmann, Anne
Author: Mitrov, Dine
Author: Groschup, Martin H
Abstract: There are only few assays available for the detection of Crimean-Congo Hemorrhagic Fever Virus (CCHFV)-specific antibodies in animals, and data about diagnostic sensitivity and specificity are incompletely documented for most of these tests. This is unfortunate since CCHFV antibodies in animals can be used as indicator for virus circulation in a geographic area and therewith potential risk of human exposure. This paper therefore reports on a novel ELISA for the detection of CCHFV-specific antibodies in cattle and on its application for testing ruminant sera from the Former Yugoslav Republic of Macedonia.
Publisher: Public Library of Science (PLoS)
Relation: PLoS neglected tropical diseases
Identifier: oai:repository.ukim.mk:20.500.12188/6343
Identifier: http://hdl.handle.net/20.500.12188/6343Identifier: 10.1371/journal.pntd.0003519
Identifier: http://dx.plos.org/10.1371/journal.pntd.0003519Identifier: 9
Identifier: 3
