Subject: Osteosarcoma
Subject: Diagnosis
Subject: Treatment
Subject: Multidisciplinary approach
Year: 2016
Type: Article
Title: MANAGEMENT OF OSTEOSARCOMA
Author: Samardjiski, Milan
Author: Nancheva, Jasminka
Author: Georgieva, Daniela
Author: Djoleva Tolevska, Roza
Author: Dalipi Rezeart
Author: Georgiev, Antonio
Abstract: Osteosarcoma is an aggressive and malignant bone tumor most commonly appearing around the knee and shoulder in adolescents and young adults. The tumors can be generally divided into those arising inside the bone and those arising on the surface of the bone. The course of the disease and its prognosis can be different. Multidisciplinary approach between orthopaedic surgeons, thoracic surgeons, radiologists, pathologists, oncologists, cardiologist and other specialist in diagnosis and treatment is mandatory. Surgical resection with wide margins after neo-adjuvant chemotherapy and adjuvant chemotherapy after surgery is a current standard of care. Applying modern chemotherapy regimen and performing limb salvage surgery calls for responsible, trained and highly engaged medical staff. If the treatment and management principles of osteosarcoma are followed, limb-sparing with 6080% survival rates can be achieved. Basic science is making continuous advance in molecular mechanisms and biologic pathways that may yield more specific agents, less-toxic drugs that will further improve overall long-term survival rates.
Publisher: MIT University Skopje
Relation: International Journal of Recent Research in Arts and Sciences
Identifier: oai:repository.ukim.mk:20.500.12188/29877
Identifier: http://hdl.handle.net/20.500.12188/29877
