Year: 2021
Type: Article
Title: Influence of alendronate therapy on the results of densitometric examination after implantation of total hip endoprosthesis
Author: Shabani, Ilir
Author: Gavrilovski, Antonio
Author: Velkovski, Vilijam
Author: Atanasov, Nenad
Author: Memeti, Shaban
Author: Belchishta, Anila
Abstract: The development of aloarthroplasty of the hip is continuously rising. After implantation of a total cement-free hip endoprosthesis, often there is a periprosthetic femoral bone loss. Alendronate has been shown to be a potent inhibitor of bone resorption activity; it inhibits osteoclastic bone resorption, increases bone mass, and plays a significant role in post-implantation stabilization of the femur. The aim of this study was to determine the effect of alendronate on osteointegration of hip endoprosthesis.Material and methods: The study analyzed 10 patients operated on with implantation of a total cement-free hip endoprosthesis (THP). The included patients were examined by a radiographic method at 6 and 12 months and DXA method at 6 and 12 months. Results: The study showed differences in the values of bone mineral density and bone mineral content in the interval between 6 and 12 months in patients undergoing THP, and hence we can conclude that alendronate therapy after THP implantation reduced periprosthetic loss of bone mass and implant stiffening. Alendronate is a proven inhibitor of periprosthetic bone loss that occurs after prirmary impantation of a total cement-free hip endoprosthesis.
Publisher: Scientific Foundation SPIROSKI
Relation: Archives of Public Health
Identifier: oai:repository.ukim.mk:20.500.12188/28262
Identifier: http://hdl.handle.net/20.500.12188/28262Identifier: 10.3889/aph.2021.5994
Identifier: https://www.id-press.eu/aph/article/download/5994/5481Identifier: https://www.id-press.eu/aph/article/download/5994/5488Identifier: https://www.id-press.eu/aph/article/download/5994/5481Identifier: 13
Identifier: 1
Identifier: 32
Identifier: 38
