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Subject: Brucellosis
Subject: spondylitis
Subject: epidemiology
Subject: endemic disease


Year: 2023


Type: Article



Title: Increased risk of brucellosis misdiagnosis in regions that lose their endemicity


Author: Bosilkovski, Mile
Author: Khezzani, Bachir
Author: Vidinic, Ivan
Author: Jakimovski, Dejan
Author: Trajanovski, D
Author: Poposki, Kostadin



Abstract: Over the last decades, the epidemiology of human brucellosis globally has been subjected to significant changes, with the eradication of many existing endemic hot spots. This paper describes three cases with initial misdiagnosis of brucellosis that were managed during 2011-2017 in Republic of North Macedonia, country that until recently has been declared as endemic region. In spite of the fever, constitutional symptoms, focal disease (spondylitis, pneumonia and orchitis) and previous contact with domestic animals, brucellosis was not initially recognized, and patients were inadequately managed. Brucellosis should be part of differential diagnostic considerations in patients exposed to contacts with animals, with osteoarticular symptoms and signs, constitutional manifestations and different organ involvements in endemic regions where its incidence is diminishing.


Publisher: Malaysian Society of Parasitology and Tropical Medicine


Relation: Tropical Biomedicine



Identifier: oai:repository.ukim.mk:20.500.12188/26384
Identifier: http://hdl.handle.net/20.500.12188/26384



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Increased risk of brucellosis misdiagnosis in regions that lose their endemicity202331