Subject: Hirayama disease
Subject: phenotype
Year: 2021
Type: Article
Title: Case report of a patient with Morbus Hirayama - presentation, diagnosis and differential diagnostic aspects
Author: Teodor Angelov
Author: Teodora Chamova
Author: Dora Zlatareva
Author: Nevena Fileva
Author: Ivan Barbov
Author: Ivailo Tournev
Abstract: Hirayama disease, also known as monomelic amyotrophy, is a rare disease characterized by slowly progressive muscle weakness and atrophy in one upper limb, most commonly in the muscles groups of the forearm and wrist. In addition to taking a detailed neurological status, electromyography (EMG) and magnetic resonance imaging (MRI) of the cervical region, native and after contrast enhancement of the image, in a neutral position and flexion, play a key role in the diagnosis process. In terms of differential diagnostic, more common disorders such as amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA) and advanced carpal tunnel syndrome should be considered. We report „Hirayama disease” in a 16-year-old female who presented with gradual right upper limb weakness and wasting in the distal muscles, that was confirmed by electrophysiological and neuroimaging studies.
Publisher: Bugarian Society of Neurology
Relation: Bulgarian Neurology
Identifier: oai:repository.ukim.mk:20.500.12188/26069
Identifier: http://hdl.handle.net/20.500.12188/26069Identifier: https://www.nevrologiabg.com/journal/index.php/neurology/article/view/97
