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Subject: primary prevention
Subject: secondary prevention
Subject: anticoagulation therapy
Subject: direct oral anticoagulants
Subject: rivaroxaban
Subject: atrial fibrillation
Subject: ischemic stroke
Subject: haemorrhagic stroke


Year: 2022


Type: Article



Title: Generation X- Challenges in anticoagulation


Author: Arsovska, Anita
Author: Pejkov, Hristo
Author: Poposka, Lidija
Author: Doneva, Ana
Author: Angelova, Aleksandra
Author: Rexhepi, Arbana
Author: Hristovska, Galina
Author: Hroneska, Elizabeta
Author: Chelikikj, Ana
Author: Bojkovska Kanevche, Tamara
Author: Manev, Nikola
Author: Vrajnko, Elif
Author: Gashpar, Glorija



Abstract: Atrial fibrillation (AF) increases an individual’s risk of stroke by 4 to 6 times on average. The risk increases with age. In people over 80 years old, AF is the direct cause of 1 in 4 strokes. In these cases, anticoagulation therapy is recommended for primary prevention and secondary stroke prevention. Direct oral anticoagulants(DOACs) such asRivaroxaban are preferred over Vitamin K antagonists(VKA), according to the latest guidelines.To presentinteresting and challenging cases from the clinical practice and discuss use of Rivaroxaban in primary and secondary prevention in patients with AFand stroke.In November 2022 we organized a two-day workshop, under the auspices of the pharma company Bayer d.o.o. Ljubljana-Representative Office Skopje, Macedonia. Neurology and Cardiologyresidents presented 10 clinical cases, under the mentorship of respective specialists, experts in theirfields. Clinical features, laboratoryanalysis,neuroimaging findings and contemporary management of each case were discussed in detail. Designated mentors presented the latest guidelines and recommendations regarding use of Rivaroxaban in primary and secondary prevention in patients with AFand stroke.Belowwe present 10 clinical cases and describe in detail their physical and neurological condition, laboratory and imaging findings and therapeutic approach


Publisher: Faculty of Medicine, Ss. Cyril and Methodius University in Skopje


Relation: Academic Medical Journal



Identifier: oai:repository.ukim.mk:20.500.12188/25542
Identifier: http://hdl.handle.net/20.500.12188/25542
Identifier: 10.53582/AMJ2222139a



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Generation X- Challenges in anticoagulation202234