Subject: T-cell Acute Lymphoblastic Leukemia
Subject: flow cytometry
Subject: cerebrospinal fluid
Year: 2013
Type: Article
Title: FLOW CYTOMETRY DIAGNOSIS OF (CD4+/CD8+) T CELL LYMPHOBLASTIC LEUKEMIA ASSOCIATED WITH NORMAL KARYOTYPE - CASE REPORT
Author: Trajkova, Sanja
Author: Chevrevska, Lidija
Author: Ivanovski, Martin
Author: Dukovski, Dushko
Author: Simjanovska-Popova, Marija
Author: Panovska Stavridis, Irina
Abstract: Adult T-cell leukemia/lymphoma (ATLL) is a peripheral T-cell neoplasm caused by human T-cell lymphotropic virus type I (HTLV-I). The neoplastic cells are highly pleomorphic and are usually CD4+ and CD8- phenotypically, but some rare cases have unusual immmunophenotype presented by co-expression of CD4/CD8 double positive cells. We present a rare case of a patient with T cell lymphoblastic leukemia associated with double-positive (CD4+/CD8+) blast cells. The diagnose was accessed with multiparameter immunophenotyping by flow cytometry analyses of bone marrow, and for the first time in our country, we confirmed isolated relapse of double-positive (CD4+/CD8+) T cell lymphoblastic leukemia in CNS
Publisher: Radiance Research Academy
Relation: International Journal of Current Research and Review
Identifier: oai:repository.ukim.mk:20.500.12188/23493
Identifier: http://hdl.handle.net/20.500.12188/23493Identifier: 5
Identifier: 8
