Subject: Ischemia Modified Albumin
Subject: Pentraxin
Subject: Pediatric
Subject: Appendicitis
Year: 2022
Type: Article
Title: Diagnostic Value of The Ischemia Modified Albumin and Pentraxin 3 In Pediatric Appendicitis: A Meta Analysis
Author: Diego Falchi
Author: Ayten Ceren Bakir
Author: Risteski, Toni
Author: Hani Abu Tziam
Author: Seçil Yüksel
Author: Sena Inal Azizoğlu
Abstract: Objective: In this meta-analysis, we aimed to review the diagnostic value of pentraxin 3 (PTX3) and ischemia-modified albumin (IMA) biomarkers in pediatric appendicitis. Method: Studies focusing on the value of PTX3 and IMA in the diagnosis of appendicitis were searched related to the PubMed database. Only randomized prospective clinical trials were included in this study. Results: After the screening, 6 articles based on the diagnostic value of IMA in appendicitis and 5 articles on the diagnostic value of PTX3 were reviewed. A total of 5 studies were included. The data of the 385 patients were reviewed. Sensitivity of PTX3 was 73-92% and specificity 88-100%, while IMA sensitivity was 89-96.7% and specificity was 26- 99.7% in acute appendicitis. Conclusion: Although the results of the present study indicate that PTX3 and IMA can be shown as biomarkers in the differential diagnosis of acute abdomen, further study is needed to determine the cut-off value
Publisher:
Relation: JOURNAL OF CLINICAL TRIALS AND EXPERIMENTAL INVESTIGATIONS (JCTEI)
Identifier: oai:repository.ukim.mk:20.500.12188/21906
Identifier: http://hdl.handle.net/20.500.12188/21906Identifier: 10.5281/zenodo.6857498
