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Subject: Aflatoxin M1, Milk, Dairy Products, Risk Assessment, Republic of North Macedonia


Year: 2022


Type: Article



Title: Dietary Exposure and Health Risk Assessment of Aflatoxin M1 in Dairy Products Consumed by Population in North Macedonia


Author: Gordana Ilievska
Author: Biljana Stojanovska-Dimzoska
Author: Dushica Koceva
Author: Goran Stojkovic
Author: Aleksandra Angeleska
Author: Elizabeta Dimitrieska-Stojkovikj



Abstract: Background: Aflatoxins (AFs), as secondary metabolites, are mainly produced by fungi of Aspergillus genus. The determination of contamination rate, dietary exposure, and health risk assessment for aflatoxin M1 (AFM1) was conducted aimed to estimate potential health risks for the population of North Macedonia. Methods: A total of 974 dairy samples, including 404 Ultra-High Temperature (UHT) milk, 291 ice cream, 178 yogurt, and 101 cheese were collected from the markets in North Macedonia. Analysis of AFM1 was done using Enzyme-Linked Immunosorbent Assay and High-Performance Liquid Chromatography with Fluorescence Detection Results: The AFM1 incidence was highest in yogurt samples (93.8%) and lowest in UHT milk samples (67.8%). AFM1 concentrations were 49.1±68.4, 30.9±30.0, 35.1±40.4, and 40.1±90.1 ng/kg for UHT milk, ice cream, yogurt, and cheese samples, respectively. The Estimated Daily Intake (EDI) for the average population and high consumers (upper bound; samples with AFM1


Publisher: Shahd Sadoughi University of Medical Sciences@ Health Services


Relation: Journal of food quality and hazard control



Identifier: oai:repository.ukim.mk:20.500.12188/21389
Identifier: http://hdl.handle.net/20.500.12188/21389
Identifier: 10.18502/jfqhc.9.1.9686



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Dietary Exposure and Health Risk Assessment of Aflatoxin M1 in Dairy Products Consumed by Population in North Macedonia202222