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Subject: foetus
Subject: malformation
Subject: teratoma


Year: 2016


Type: Proceeding article



Title: Foetus acardius amorphous - report of two cases


Author: Gjorgjievska, Aneta
Author: Ristovski, Gligor
Author: Zdravkovski, Panche
Author: Kostadinova Kunovska, Slavica
Author: Spasevska, Liljana
Author: Petrushevska, Gordana



Abstract: Objective: Foetus acardius amorphous is a rare congenital malformation with an incidence of 1:35000 births, which usually is a complication in multiple pregnancies. The main diagnostic dilemma is placental teratoma, a non-trophoblastic, extremely rare tumor, with only 27 cases reported in the literature. We present a case of a triplet pregnancy of a 35-year-old mother and a twin pregnancy of a 32-year old mother. Material and Methods: Case 1. Along with three live births, there was a teratogenic, skin-covered, oval tumor mass, weighing 1450 grams and 21x15x6 cm in size, with two epidermal buds with a diameter of 2-3 cm on the surface. On dissection, there were fatty tissue, muscle, cartilage, bone and large intestinal loops. Case 2. Along with a stillbirth, there was an oval, skin-covered structure weighing 67 grams and diameter of 9.5 cm, with visible elongated bud, resembling a limb, at one pole. The dissection showed autolytic organoid structures and cavities. Results: There are a few criteria for differentiating acardiac fetus from placental teratoma: a presence of umbilical cord, skeletal structures, visible rudimentary extremities and partially developed visceral organs. On the other hand, a placental teratoma is predominantly composed of a disorganized collection of mature tissues. The gross and histological findings solved our diagnostic dilemma. Conclusions: There is a great overlap between these two entities and the proposed criteria are useful only in clear cases. Some authors consider them as different levels of development and differentiation of a single pathological event. Nonetheless, the clinical information for multiple gestation pregnancies is very important and helpful for diagnosing foetus acardiacus.


Publisher: Macedonian Association of Pathology


Relation: Proceedings and Abstract Book



Identifier: oai:repository.ukim.mk:20.500.12188/17780
Identifier: http://hdl.handle.net/20.500.12188/17780
Identifier: Proceeding & Abstracts Book, 2016:127



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Foetus acardius amorphous - report of two cases201615