Subject: recurrent venous thromboembolism
Subject: thrombophilia
Subject: psoriasis
Subject: pulmonary embolism
Year: 2020
Type: Article
Title: DEEP VEIN THROMBOSIS AND RECURENT PULMONARY EMBOLISM IN A PATIENT WITH THROMBOPHILIC MUTATIONS AND GENERALIZED PSORIASIS: A CASE REPORT
Author: Baloski, Marjan
Author: Buklioska Ilievska, Daniela
Author: Brishkoska Boshkovski, Vesna
Author: Hasan, Taner
Author: Nedeska Minova, Natasha
Author: Prgova-Veljanova, Biljana
Author: Nanceva Bogoevska, Andrea
Author: Nancheva, Jasminka
Author: Bosevski, Marijan
Author: Panov, Saso
Abstract: Introduction: Genetic risk factors that increase venous thromboembolism risk are disorders in the synthesis or activity of coagulation factors. Fac- tor V Leiden, prothrombin (20210-A), antithrombin deficiency, protein C and protein S deficiency, and hyperhomocysteinaemia are the most common venous thromboembolism-related gene mutations. When ge- netic factors are combined with non-provoking risk factors (obesity, psoriasis, smoking and previous veno- us thromboembolism) the result is increased venous thromboembolism risk for each factor individually. Previous venous thromboembolism is one of the stron- gest risk factors, even in patients actively treated with anticoagulant. Patients are more likely to have recur- rent venous thromboembolism with longer duration. Psoriasis is a complex immune–mediated disease, as- sociated with cardiovascular risk, hypercoagulability markers and elevated homocysteine. Lots of observati- onal reports suggest increased incidence of venous trombembolic events in patient with psoriasis
Publisher: Association of medical doctors "Sanamed" Novi Pazar
Relation: SANAMED
Identifier: oai:repository.ukim.mk:20.500.12188/16500
Identifier: http://hdl.handle.net/20.500.12188/16500Identifier: 10.24125/sanamed.v15i2.391
Identifier: 15
Identifier: 2
Identifier: 183
