Subject: diabetes mellitus
Subject: lipoprotein(a)
Subject: cardiovascular risk factors
Year: 2017
Type: Article
Title: Are diabetes mellitus and lipoprotein(a) independently or causally associated with an increased cardiovascular risk?
Author: Marija Vavlukis
Abstract: Serum Lp(a) and diabetes mellitus increase the risk of cardiovascular diseases (CVD). However, the relationship between serum Lp(a) and diabetes is poorly characterized, and it is a subject of debate as to whether they are independently or causally associated (1). One of the atherogenic mechanisms in hyperglycemia is based on enhanced inflammation. Diabetes is associated with increased vascular production of reactive oxygen species (ROS), which causes premature cell apoptosis via reduction of endothelial nitric oxide (NO), resulting in decreased smooth muscle relaxation and antiatherogenic properties, including decreased platelet aggregation and adhesion inhibition (1).
Publisher: Kare (Turkey)
Relation: Anatolian journal of cardiology
Identifier: oai:repository.ukim.mk:20.500.12188/13703
Identifier: Vavlukis M. Are diabetes mellitus and lipoprotein(a) independently or causally associated with an increased cardiovascular risk? Anatol J Cardiol. 2017 Mar;17(3):200-201. doi: 10.14744/AnatolJCardiol.2017.23434. PMID: 28321108; PMCID: PMC5864979.
Identifier: http://hdl.handle.net/20.500.12188/13703Identifier: 17
Identifier: 3
