Subject: Hodgkin's lymphoma
Subject: chronic lymphocytic leukemia
Subject: second malignancies
Year: 2017
Type: Article
Title: Chronic lymphocytic leukemia following successfull treatment of Hodgkin’s lymphoma: report of two patients
Author: Gazmend Amzai
Author: Oliver Karanfilski
Author: Tatjana Sotirova
Author: Sonja Genadieva-Stavric
Author: Arif Latifi
Author: Aleksandar Stojanovic
Abstract: Over the past few decades, introducing effective therapy, improved staging procedures, and significant improvement of supportive measures, significantly improved the prospects for patients with Hodgkin's lymphoma, leading to a 75-90% cure rate. Hodgkin's lymphoma survivors are at high risk of developing a large variety of second malignant neoplasms. It is crucial to maintain awareness regarding this issue. The subsequent development of Chronic Lymphocytic Leukemia (CLL) in patients after successful treatment of Hodgkin's lymphoma (HL) is an extremely rare possibility. The relationship between these two lymphoproliferative disorders is unclear. Herein we describe two cases of CLL, developed in previously treated patients with HL, with characterization of two distinct lymphoproliferative disease in these two patients. We also systematically reviewed the existing literature on this very rare occurrence of treatment-induced second hematological malignancies.
Publisher: Македонско лекарско друштво = Macedonian Medical Association
Relation: Македонски медицински преглед = Macedonian Medical Review
Identifier: oai:repository.ukim.mk:20.500.12188/11501
Identifier: Gazmend Amzai, Oliver Karanfilski, Tatjana Sotirova, Sonja Genadieva-Stavric, Arif Latifi and Aleksandar Stojanovic. Chronic lymphocytic leukemia following successfull treatment of Hodgkin’s lymphoma: report of two patients.Mac.Med.Review 2017; 71 (3): 212-214.
Identifier: ISSN: 0025-1097
Identifier: http://hdl.handle.net/20.500.12188/11501Identifier: 71
Identifier: 3
Identifier: 212
