Subject: vertebral fractures
Subject: rheumatoid arthritis
Subject: glucocorticoids
Subject: osteoporosis
Year: 2020
Type: Reference Book
Title: Аssessment of osteoporosis and occurrence of vertebral fractures in postmenopausal patients with rheumatoid arthritis treated with small doses of glucocorticoids
Author: Bojadzioska, Maja
Author: Dejanov, Petar
Author: Kafedзiska, Irena
Author: Nikolovska-Kotevska, Mimoza
Author: Karadzova-Stojanoska, Andzelika
Author: Isjanovski, Viktor
Author: Jovanovska Mishevska, Sasha
Author: Gucev, Filip
Author: Isjanovski, Igor
Author: Curakova Ristovska, Elena
Abstract: Osteoporosis (OP) is a serious extracorporeal manifestation that occurs in patients with rheumatoid arthritis (RA). One of the risk factors is long-term use of glucocorticoids (GC). Osteoporosis together with the increased risk of vertebral (VF) and non-vertebral fractures (non-VF) in particular has a negative impact on quality of life in patients with rheumatoid arthritis. The aim of the study was to detect the occurrence of OP and VF in postmenopausal patients with RA and their association with long-term use of small doses of glucocorticoids. Material and methods: A total of 46 patients were analyzed. All respondents underwent imaging for osteoporosis evaluation with a DXA scanner (Lunar iDXA, GE) and VF with incorporated Vertebral Fracture Assessment (VFA). Results: The values of bone mineral densities (BMD) were significantly smaller in the group that received glucocorticoids. According to VFA, 37,0% of patients were registered to have a fracture of middle degree, a mild fracture was registered in 19.6% of patients, and severe fractures were registered in 3 patients (6.5%). Conclusion: In postmenopausal patients with RA receiving GC therapy, a more common occurrence of osteoporosis and vertebral fractures was reported compared with the remaining group of RA patients. All patients with RA in menopause need to be screened for timely detection and treatment of osteoporosis and prevention of its complications.
Publisher: Институт за јавното здравје на Република Македонија = Institute of public health of the Republic of Macedonia
Relation: Архиви на јавното здравје = Archives of Public Health
Identifier: oai:repository.ukim.mk:20.500.12188/10910
Identifier: http://hdl.handle.net/20.500.12188/10910Identifier: 10.3889/aph.2020.5608
Identifier: https://www.id-press.eu/aph/article/download/5608/5333Identifier: https://www.id-press.eu/aph/article/download/5608/5333Identifier: 12
Identifier: 3
