Subject: Other medical sciences
Year: 2023
Type: Conference or Workshop Item
Type: PeerReviewed
Title: Design of Feasibility Study for the Establishment of 89Zr Production – Tailored Approach to Introduce New Radiopharmaceuticals in a Developing Country
Author: Kolevska, Katerina
Author: Cocevska, Maja
Author: Atanasova, Marija
Author: Velickovska, Maja
Author: Jolevski, Filip
Author: Angelovska, Bistra
Author: Ugrinska, Ana
Abstract: Establishing radiopharmaceutical production in a developing country is challenging, mainly in the economic aspect. A feasibility study provides an objective insight into many aspects of the feasibility of the idea of introducing new radiopharmaceutical. The feasibility study for establishing production of 89Zr is designed to include preliminary analysis, market research, technical feasibility analysis, economic analysis, review and analysis of all data, and feasibility conclusion. The preliminary analysis comprises a review of the application of 89Zr radiopharmaceuticals in clinical trials and a review of the cancer statistics on a national level. The technical feasibility determination is based on the analysis of the technical capacities of the production site – University Institute of Positron Emission Tomography. The economic feasibility estimation comprehends financial and pharmacoeconomic analysis, which aims to assess the justification for implementing a new radiopharmaceutical in clinical practice. For this purpose, a cost-effectiveness analysis is performed. 89Zr-trastuzumab is selected as a subject of the pharmacoeconomic estimation, based on the results of the preliminary analysis: 89Zr-trastuzumab is one of the most common 89Zr-radiopharmaceuticals in clinical trials, and on the national level the breast cancer is the most common malignancy and the most common cause of death from cancers in the female population
Publisher:
Relation: https://eprints.ugd.edu.mk/34369/
Identifier: oai:eprints.ugd.edu.mk:34369
Identifier: https://eprints.ugd.edu.mk/34369/1/284%20Katerina%20ISTR%20.pdfIdentifier: https://eprints.ugd.edu.mk/34369/2/Kolevska%20K%20ISTR%202023.pdfIdentifier: Kolevska, Katerina and Cocevska, Maja and Atanasova, Marija and Velickovska, Maja and Jolevski, Filip and Angelovska, Bistra and Ugrinska, Ana (2023) Design of Feasibility Study for the Establishment of 89Zr Production – Tailored Approach to Introduce New Radiopharmaceuticals in a Developing Country. In: International Symposium on Trends in Radiopharmaceuticals (ISTR-2023), 17-21 Apr 2023, Vienna, Austria.
