Subject: Clinical medicine
Year: 2023
Type: Article
Type: PeerReviewed
Title: Covid-19 in children with Down syndrome - case series
Author: Ivanovska, Julija
Author: Nestorov, Hristijan
Author: Popova, Gorica
Author: Chakalarovska, Irena
Author: Petlichkovska, Sandra
Author: Boshkovska, Katerina
Abstract: Down syndrome (DS) is the most common genetic disease and presents with cognitive impairment, cardiac and gastrointestinal abnormalities, increased risk of hematological malignancy and several autoimmune conditions in addition to other miscellaneous clinical conditions The aim is to show if the comorbidities that children with Down Sy have, were risk factors for more severe form of COVID-19. We present three cases of children with Down Sy and COVID-19, with different clinical features. All of them had good clinical outcome, only the first child had more severe form of Covid 19 with need for oxygen support, longer hospitalization but with good clinical improvement and withdrawal of the X-ray changes. Children with Down Sy are always a high-risk group for more severe and prolonged course of disease, which are partially attributed to defects of the immune system.
Publisher: Macedonian Association of Anatomists
Relation: https://eprints.ugd.edu.mk/32991/
Identifier: oai:eprints.ugd.edu.mk:32991
Identifier: https://eprints.ugd.edu.mk/32991/1/505-1-2311-2-10-20231118.pdfIdentifier: Ivanovska, Julija and Nestorov, Hristijan and Popova, Gorica and Chakalarovska, Irena and Petlichkovska, Sandra and Boshkovska, Katerina (2023) Covid-19 in children with Down syndrome - case series. Journal of Morphological Sciences, Vol 6 (2). pp. 93-97. ISSN 2545-4706