Subject: Basic medicine
Subject: Chemical engineering
Subject: Chemical sciences
Subject: Materials engineering
Subject: Nano-technology
Year: 2021
Type: Conference or Workshop Item
Type: PeerReviewed
Title: The role of Crystal Engineering in designing functional materials (perspective for Pharmaceutical cocrystals)
Author: Cvetkovski, Aleksandar
Author: Drakalska, Elena
Author: Duvlis, Sotirija
Author: Angelovska, Bistra
Abstract: Crystal engineering cover the most recent advances in process-dependent properties of functional materials, concerning not only correlations between crystal growth process and characterization, but also growth process design strategy for their enhanced functional and smart properties to be applied in various type of functional materials exhibiting interesting optical, electronic, magnetic, catalytic and mechanical properties that offer wide range of their application in energy, healthcare, electronics, engineering and catalysis. In the past decade, pharmaceutical cocrystals have demonstrated significant promise in their ability to modify the physicochemical and pharmacokinetic properties of drug substances, such as the solubility and dissolution rate, bioavailability, particle morphology and size, tableting and compaction, melting point, physical form, biochemical and hydration stability, and permeability. Manipulating on the noncovalent interactions, established in controlled conduction of processing the solid phases, it is possible to alter the packing motifs that consequently lead to macroscopic solid phases with modulated properties comparing to native substance. Keywords: Crystal engineering, molecular recohnition, pharmaceutical multicomponent solids
Publisher:
Relation: https://eprints.ugd.edu.mk/28432/
Identifier: oai:eprints.ugd.edu.mk:28432
Identifier: https://eprints.ugd.edu.mk/28432/1/GSU_Conference%20Book_2021%28Pdf%29.pdfIdentifier: https://eprints.ugd.edu.mk/28432/2/GSU_Conference_Programme%20%28May%2C2021%29.pdfIdentifier: Cvetkovski, Aleksandar and Drakalska, Elena and Duvlis, Sotirija and Angelovska, Bistra (2021) The role of Crystal Engineering in designing functional materials (perspective for Pharmaceutical cocrystals). In: International Scientific Conference on the “Actual problems of the natural science" dedicated to 98th anniversary of National leader heydar Aliyev, 06-07 May 2021.
